1- Department of Criminology, Shiraz Branch, Islamic Azad University, Shiraz, Iran
2- Legal Medicine Research Center, Iranian Legal Medicine Organization, Tehran, Iran
3- Legal Medicine Research Center, Iranian Legal Medicine Organization, Tehran, Iran , fleglaresearch@gmail.com |
Introduction: Considering the legalization of marijuana use in some countries and regions, its health effects and side effects have been investigated in scientific studies. In this review study, the health benefits and possible side effects of marijuana were investigated.
Methods: In a systematic review, all valid studies that investigated the side effects and therapeutic benefits of marijuana were analyzed. The search for articles and theses in Iranian sources was conducted in Medline, PubMed, Web of Science and Embase, Scopus, and Google Scholar by searching for keywords Marijuana, Therapy, Treatment, Therapeutics and side effects from 2010 to 2022. Also, the reference list of all the articles that were identified in the first steps was reviewed in order to obtain the cited articles that were not found by the electronic searches.
Results: The findings of this study showed that marijuana increases energy and improves the quality of sleep, improves mood, improves appetite, calorie intake, sense of taste and perception of taste in cancer patients, increases the quality of sleep and relaxes the quality of life, improves pain control in It is effective for patients with chronic pain, relieving muscle spasm, treating chronic and neuropathic pain, treating symptoms in MS, and improving symptoms of inflammatory bowel disease (IBD). Also, anti-vomiting effects and improvement of quality in cancer patients, anti-cancer activity, treatment of anxiety and insomnia caused by PTSD in children, increase in general quality of life, mobility and mood, by reducing inflammation, intraocular pressure, spasm, convulsions, Treatment of pain, headache and migraine and in patients with MS plays a role in reducing the severity of the disease, stiffness of the hind limbs, motor function, neuroinflammation and demyelination. However, this substance may have side effects such as cognitive impairment, drowsiness, dizziness, dependence and addiction, as well as the possibility of fungal infection in patients with immune suppression.
Conclusion: Although marijuana has some known therapeutic contraindications and side effects, to ensure the therapeutic uses of marijuana, double-blind clinical tests are recommended in specific treatment target groups. |
